Beilstein J. Org. Chem.2014,10, 1099–1106, doi:10.3762/bjoc.10.108
synthetically valuable tetrasubstituted CF3-alkenes are obtained, have never been reported so far. Remarkably, the present facile and straightforward protocol is extended to double trifluoromethylation of alkenes.
Keywords: electrophilic trifluoromethylating reagent; multi-substitutedalkene; photoredox
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Graphical Abstract
Scheme 1:
Representative examples of multisubstituted CF3-alkenes.